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Acidic fibroblast growth factor underlies microenvironmental regulation of MYC in pancreatic cancer
Despite a critical role for MYC as an effector of oncogenic RAS, strategies to target MYC activity in RAS-driven cancers are lacking. In genetically engineered mouse models of lung and pancreatic cancer, oncogenic KRAS is insufficient to drive tumorigenesis, while addition of modest MYC overexpressi...
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| Publicado no: | J Exp Med |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7398167/ https://ncbi.nlm.nih.gov/pubmed/32434218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191805 |
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