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Deconstructing Pancreatic Adenocarcinoma by Targeting the Conductor, MYC
In this issue of Cancer Discovery , Sodir and colleagues employ a pancreatic ductal adenocarcinoma mouse model with mutant KRAS and inducible MYC to demonstrate that MYC acts as a reversible driver of malignant tumor progression. Abrogation of MYC triggers rapid regression and disassembly of the ens...
Shranjeno v:
| izdano v: | Cancer Discov |
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| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7902157/ https://ncbi.nlm.nih.gov/pubmed/32238397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-20-0046 |
| Oznake: |
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