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Deconstructing Pancreatic Adenocarcinoma by Targeting the Conductor, MYC

In this issue of Cancer Discovery , Sodir and colleagues employ a pancreatic ductal adenocarcinoma mouse model with mutant KRAS and inducible MYC to demonstrate that MYC acts as a reversible driver of malignant tumor progression. Abrogation of MYC triggers rapid regression and disassembly of the ens...

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Sonraí Bibleagrafaíochta
Foilsithe in:Cancer Discov
Main Authors: English, Isabel A., Sears, Rosalie C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902157/
https://ncbi.nlm.nih.gov/pubmed/32238397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-20-0046
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