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m(6)A-RNA Demethylase FTO Inhibitors Impair Self-Renewal in Glioblastoma Stem Cells

[Image: see text] N(6)-methyladenosine (m(6)A) has emerged as the most abundant mRNA modification that regulates gene expression in many physiological processes. m(6)A modification in RNA controls cellular proliferation and pluripotency and has been implicated in the progression of multiple disease...

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Publicat a:ACS Chem Biol
Autors principals: Huff, Sarah, Tiwari, Shashi Kant, Gonzalez, Gwendolyn M., Wang, Yinsheng, Rana, Tariq M.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2021
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901021/
https://ncbi.nlm.nih.gov/pubmed/33412003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00841
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