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m(6)A-RNA Demethylase FTO Inhibitors Impair Self-Renewal in Glioblastoma Stem Cells

[Image: see text] N(6)-methyladenosine (m(6)A) has emerged as the most abundant mRNA modification that regulates gene expression in many physiological processes. m(6)A modification in RNA controls cellular proliferation and pluripotency and has been implicated in the progression of multiple disease...

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Détails bibliographiques
Publié dans:ACS Chem Biol
Auteurs principaux: Huff, Sarah, Tiwari, Shashi Kant, Gonzalez, Gwendolyn M., Wang, Yinsheng, Rana, Tariq M.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2021
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901021/
https://ncbi.nlm.nih.gov/pubmed/33412003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00841
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