m(6)A-RNA Demethylase FTO Inhibitors Impair Self-Renewal in Glioblastoma Stem Cells

[Image: see text] N(6)-methyladenosine (m(6)A) has emerged as the most abundant mRNA modification that regulates gene expression in many physiological processes. m(6)A modification in RNA controls cellular proliferation and pluripotency and has been implicated in the progression of multiple disease...

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Bibliographic Details
Published in:ACS Chem Biol
Main Authors: Huff, Sarah, Tiwari, Shashi Kant, Gonzalez, Gwendolyn M., Wang, Yinsheng, Rana, Tariq M.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2021
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901021/
https://ncbi.nlm.nih.gov/pubmed/33412003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00841
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