Učitavanje...
The histone demethylase Jarid1b is required for hematopoietic stem cell self-renewal in mice
Jarid1b/KDM5b is a histone demethylase that regulates self-renewal and differentiation in stem cells and cancer; however, its function in hematopoiesis is unclear. Here, we find that Jarid1b is highly expressed in primitive hematopoietic compartments and is overexpressed in acute myeloid leukemias....
Spremljeno u:
| Izdano u: | Blood |
|---|---|
| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society of Hematology
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4467872/ https://ncbi.nlm.nih.gov/pubmed/25655602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-08-596734 |
| Oznake: |
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