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Prime Editing Guide RNA Design Automation Using PINE-CONE

[Image: see text] CRISPR-based technologies are paramount in genome engineering and synthetic biology. Prime editing (PE) is a technology capable of installing genomic edits without double-stranded DNA breaks (DSBs) or donor DNA. Prime editing guide RNAs (pegRNAs) simultaneously encode both guide an...

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Bibliografiska uppgifter
I publikationen:ACS Synth Biol
Huvudupphovsmän: Standage-Beier, Kylie, Tekel, Stefan J., Brafman, David A., Wang, Xiao
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Chemical Society 2021
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901017/
https://ncbi.nlm.nih.gov/pubmed/33464043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.0c00445
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