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Prime Editing Guide RNA Design Automation Using PINE-CONE
[Image: see text] CRISPR-based technologies are paramount in genome engineering and synthetic biology. Prime editing (PE) is a technology capable of installing genomic edits without double-stranded DNA breaks (DSBs) or donor DNA. Prime editing guide RNAs (pegRNAs) simultaneously encode both guide an...
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| Publicado no: | ACS Synth Biol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2021
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7901017/ https://ncbi.nlm.nih.gov/pubmed/33464043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.0c00445 |
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