Exosomal miR-128-3p Promotes Epithelial-to-Mesenchymal Transition in Colorectal Cancer Cells by Targeting FOXO4 via TGF-β/SMAD and JAK/STAT3 Signaling

Epithelial-to-mesenchymal transition (EMT) is a key process that occurs during tumor metastasis, affecting a variety of malignancies including colorectal cancer (CRC). Exosomes mediate cell-cell communication by transporting cell-derived proteins and nucleic acids, including microRNAs (miRNAs). Exos...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Cell Dev Biol
Auteurs principaux: Bai, Jian, Zhang, Xue, Shi, Dongdong, Xiang, Zhenxian, Wang, Shuyi, Yang, Chaogang, Liu, Qing, Huang, Sihao, Fang, Yan, Zhang, Weisong, Song, Jialin, Xiong, Bin
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Cell and Developmental Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7900423/
https://ncbi.nlm.nih.gov/pubmed/33634112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.568738
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