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A critical residue in the α(1)M2–M3 linker regulating mammalian GABA(A) receptor pore gating by diazepam
Benzodiazepines (BZDs) are a class of widely prescribed psychotropic drugs that modulate activity of GABA(A) receptors (GABA(A)Rs), neurotransmitter-gated ion channels critical for synaptic transmission. However, the physical basis of this modulation is poorly understood. We explore the role of an i...
Shranjeno v:
| izdano v: | eLife |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
eLife Sciences Publications, Ltd
2021
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7899671/ https://ncbi.nlm.nih.gov/pubmed/33591271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.64400 |
| Oznake: |
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