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Inverse Effects on Gating and Modulation Caused by a Mutation in the M2-M3 Linker of the GABA(A) Receptor γ Subunit
M2-M3 linkers are receptor subunit domains known to be critical for the normal function of cysteine-loop ligand-gated ion channels. Previous studies of α and β subunits of type “A” GABA receptors suggest that these linkers couple extracellular elements involved in GABA binding to the transmembrane s...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Pharmacology and Experimental Therapeutics
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2730393/ https://ncbi.nlm.nih.gov/pubmed/19553237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.055111 |
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