Loading...

A critical residue in the α(1)M2–M3 linker regulating mammalian GABA(A) receptor pore gating by diazepam

Benzodiazepines (BZDs) are a class of widely prescribed psychotropic drugs that modulate activity of GABA(A) receptors (GABA(A)Rs), neurotransmitter-gated ion channels critical for synaptic transmission. However, the physical basis of this modulation is poorly understood. We explore the role of an i...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Nors, Joseph W, Gupta, Shipra, Goldschen-Ohm, Marcel P
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7899671/
https://ncbi.nlm.nih.gov/pubmed/33591271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.64400
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!