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Extrahepatic cytochrome P450 epoxygenases: pathophysiology and clinical significance in human gastrointestinal cancers

Cytochrome P450 (CYP) epoxygenases, a multi-gene superfamily of heme-containing enzymes, are commonly known to metabolize endogenous arachidonic acid (AA) to epoxyeicosatrienoic acids (EETs). The role of CYPs is mostly studied in liver drugs metabolism, cardiac pathophysiology, and hypertension fiel...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Pidkovka, Nataliya, Rachkevych, Olena, Belkhiri, Abbes
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7899545/
https://ncbi.nlm.nih.gov/pubmed/33659048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27893
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