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Effects of Acetylenic Epoxygenase Inhibitors on Recombinant Cytochrome P450s

Arachidonate epoxidation, which mediates important biological functions in several tissues, is catalyzed by specific cytochrome P450 (P450) enzymes. Two fatty acid derivatives [2-(2-propynyloxy)-benzenehexanoic acid (PPOH) and N-(methylsulfonyl)-2-(2-propynyloxy)-benzenehexanamide (MS-PPOH)] are use...

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Autors principals: VanAlstine, Melissa A., Hough, Lindsay B.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127235/
https://ncbi.nlm.nih.gov/pubmed/21460231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.110.037424
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