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Effects of Acetylenic Epoxygenase Inhibitors on Recombinant Cytochrome P450s

Arachidonate epoxidation, which mediates important biological functions in several tissues, is catalyzed by specific cytochrome P450 (P450) enzymes. Two fatty acid derivatives [2-(2-propynyloxy)-benzenehexanoic acid (PPOH) and N-(methylsulfonyl)-2-(2-propynyloxy)-benzenehexanamide (MS-PPOH)] are use...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: VanAlstine, Melissa A., Hough, Lindsay B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127235/
https://ncbi.nlm.nih.gov/pubmed/21460231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.110.037424
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