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Sirolimus augments hematopoietic stem and progenitor cell regeneration following hematopoietic insults
The role of mammalian target of rapamycin and its suppressor sirolimus in the regulation of hematopoietic stem and progenitor cells (HSPCs) is controversial. We show here that sirolimus enhanced regeneration of HSPCs in mice exposed to sublethal total body irradiation (TBI) and other regenerative st...
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| 發表在: | Stem Cells |
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| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley & Sons, Inc.
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7898520/ https://ncbi.nlm.nih.gov/pubmed/33270949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3313 |
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