Sirolimus augments hematopoietic stem and progenitor cell regeneration following hematopoietic insults

The role of mammalian target of rapamycin and its suppressor sirolimus in the regulation of hematopoietic stem and progenitor cells (HSPCs) is controversial. We show here that sirolimus enhanced regeneration of HSPCs in mice exposed to sublethal total body irradiation (TBI) and other regenerative st...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Stem Cells
Autori principali: Lin, Zenghua, Hollinger, Maile K., Wu, Zhijie, Sun, Wanling, Batey, Kaylind, Kim, Jisoo, Chen, Jichun, Feng, Xingmin, Young, Neal S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2020
Soggetti:
Translational and Clinical Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898520/
https://ncbi.nlm.nih.gov/pubmed/33270949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3313
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi