Sirolimus augments hematopoietic stem and progenitor cell regeneration following hematopoietic insults

The role of mammalian target of rapamycin and its suppressor sirolimus in the regulation of hematopoietic stem and progenitor cells (HSPCs) is controversial. We show here that sirolimus enhanced regeneration of HSPCs in mice exposed to sublethal total body irradiation (TBI) and other regenerative st...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Lin, Zenghua, Hollinger, Maile K., Wu, Zhijie, Sun, Wanling, Batey, Kaylind, Kim, Jisoo, Chen, Jichun, Feng, Xingmin, Young, Neal S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Translational and Clinical Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898520/
https://ncbi.nlm.nih.gov/pubmed/33270949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3313
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados