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Macrophage TNF-α licenses donor T cells in murine bone marrow failure and can be implicated in human aplastic anemia

Interferon-γ (IFN-γ) and tumor necrosis factor-α (TNF-α) have been implicated historically in the immune pathophysiology of aplastic anemia (AA) and other bone marrow (BM) failure syndromes. We recently defined the essential roles of IFN-γ produced by donor T cells and the IFN-γ receptor in the host...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Sun, Wanling, Wu, Zhijie, Lin, Zenghua, Hollinger, Maile, Chen, Jichun, Feng, Xingmin, Young, Neal S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307988/
https://ncbi.nlm.nih.gov/pubmed/30361263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-05-844928
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