Crystal structures of the EVE-HNH endonuclease VcaM4I in the presence and absence of DNA

Many modification-dependent restriction endonucleases (MDREs) are fusions of a PUA superfamily modification sensor domain and a nuclease catalytic domain. EVE domains belong to the PUA superfamily, and are present in MDREs in combination with HNH nuclease domains. Here, we present a biochemical char...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Pastor, Michal, Czapinska, Honorata, Helbrecht, Igor, Krakowska, Katarzyna, Lutz, Thomas, Xu, Shuang-yong, Bochtler, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7897488/
https://ncbi.nlm.nih.gov/pubmed/33450012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1218
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