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Restriction endonucleases that cleave RNA/DNA heteroduplexes bind dsDNA in A-like conformation

Restriction endonucleases naturally target DNA duplexes. Systematic screening has identified a small minority of these enzymes that can also cleave RNA/DNA heteroduplexes and that may therefore be useful as tools for RNA biochemistry. We have chosen AvaII (G↓GWCC, where W stands for A or T) as a rep...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Kisiala, Marlena, Kowalska, Monika, Pastor, Michal, Korza, Henryk J, Czapinska, Honorata, Bochtler, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337904/
https://ncbi.nlm.nih.gov/pubmed/32459314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa403
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