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Calculating metalation in cells reveals CobW acquires Co(II) for vitamin B(12) biosynthesis while related proteins prefer Zn(II)
Protein metal-occupancy (metalation) in vivo has been elusive. To address this challenge, the available free energies of metals have recently been determined from the responses of metal sensors. Here, we use these free energy values to develop a metalation-calculator which accounts for inter-metal c...
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| Publicado en: | Nat Commun |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7895991/ https://ncbi.nlm.nih.gov/pubmed/33608553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21479-8 |
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