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Calculating metalation in cells reveals CobW acquires Co(II) for vitamin B(12) biosynthesis while related proteins prefer Zn(II)
Protein metal-occupancy (metalation) in vivo has been elusive. To address this challenge, the available free energies of metals have recently been determined from the responses of metal sensors. Here, we use these free energy values to develop a metalation-calculator which accounts for inter-metal c...
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| Publicat a: | Nat Commun |
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| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7895991/ https://ncbi.nlm.nih.gov/pubmed/33608553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21479-8 |
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