Imaging the mechanisms of anti-CD20 therapy in vivo uncovers spatiotemporal bottlenecks in antibody-dependent phagocytosis

Anti-CD20 antibody (mAb) represents an effective strategy for the treatment of B cell malignancies, possibly involving complement activity, antibody-dependent cellular cytotoxicity and phagocytosis (ADP). While ADP by Kupffer cells deplete circulating tumors, mechanisms targeting non-circulating tum...

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Detaylı Bibliyografya
Yayımlandı:Sci Adv
Asıl Yazarlar: Grandjean, Capucine L., Garcia, Zacarias, Lemaître, Fabrice, Bréart, Béatrice, Bousso, Philippe
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Association for the Advancement of Science 2021
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7895428/
https://ncbi.nlm.nih.gov/pubmed/33608271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abd6167
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