The mechanism of anti-CD20–mediated B cell depletion revealed by intravital imaging

Anti-CD20 Ab therapy has proven successful for treating B cell malignancies and a number of autoimmune diseases. However, how anti-CD20 Abs operate in vivo to mediate B cell depletion is not fully understood. In particular, the anatomical location, the type of effector cells, and the mechanism under...

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Detaylı Bibliyografya
Asıl Yazarlar: Montalvao, Fabricio, Garcia, Zacarias, Celli, Susanna, Breart, Béatrice, Deguine, Jacques, Van Rooijen, Nico, Bousso, Philippe
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2013
Konular:
Brief Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859399/
https://ncbi.nlm.nih.gov/pubmed/24177426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70972
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