Naked mole rat TRF1 safeguards glycolytic capacity and telomere replication under low oxygen

The naked mole rat (NMR), a long-lived and cancer-resistant rodent, is highly resistant to hypoxia. Here, using robust cellular models wherein the mouse telomeric protein TRF1 is substituted by NMR TRF1 or its mutant forms, we show that TRF1 supports maximal glycolytic capacity under low oxygen, sho...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Adv
Principais autores: Augereau, Adeline, Mariotti, Marco, Pousse, Mélanie, Filipponi, Doria, Libert, Frédérick, Beck, Benjamin, Gorbunova, Vera, Gilson, Eric, Gladyshev, Vadim N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7895426/
https://ncbi.nlm.nih.gov/pubmed/33608273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe0174
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados