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α-synuclein impairs autophagosome maturation through abnormal actin stabilization

Vesicular trafficking defects, particularly those in the autophagolysosomal system, have been strongly implicated in the pathogenesis of Parkinson’s disease and related α-synucleinopathies. However, mechanisms mediating dysfunction of membrane trafficking remain incompletely understood. Using a Dros...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS Genet
मुख्य लेखकों: Sarkar, Souvarish, Olsen, Abby L., Sygnecka, Katja, Lohr, Kelly M., Feany, Mel B.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7895402/
https://ncbi.nlm.nih.gov/pubmed/33556113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009359
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