Comparative proteomic analysis highlights metabolic dysfunction in α-synucleinopathy

The synaptic protein α-synuclein is linked through genetics and neuropathology to the pathogenesis of Parkinson’s disease and related disorders. However, the mechanisms by which α-synuclein influences disease onset and progression are incompletely understood. To identify pathogenic pathways and ther...

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Bibliografiske detaljer
Udgivet i:NPJ Parkinsons Dis
Main Authors: Sarkar, Souvarish, Murphy, Michael A., Dammer, Eric B., Olsen, Abby L., Rangaraju, Srikant, Fraenkel, Ernest, Feany, Mel B.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732845/
https://ncbi.nlm.nih.gov/pubmed/33311497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41531-020-00143-w
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