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α-synuclein impairs autophagosome maturation through abnormal actin stabilization
Vesicular trafficking defects, particularly those in the autophagolysosomal system, have been strongly implicated in the pathogenesis of Parkinson’s disease and related α-synucleinopathies. However, mechanisms mediating dysfunction of membrane trafficking remain incompletely understood. Using a Dros...
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| Publicado no: | PLoS Genet |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7895402/ https://ncbi.nlm.nih.gov/pubmed/33556113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009359 |
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