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Concentration‐QTc Modeling of Ozanimod’s Major Active Metabolites in Adult Healthy Subjects
Ozanimod, approved by regulatory agencies in multiple countries for the treatment of adults with relapsing multiple sclerosis, is a sphingosine 1‐phosphate (S1P) receptor modulator, which binds with high affinity selectively to S1P receptor subtypes 1 and 5. The relationships between plasma concentr...
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| Publicado no: | CPT Pharmacometrics Syst Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7894403/ https://ncbi.nlm.nih.gov/pubmed/33314790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12580 |
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