No QTc Prolongation With Zanubrutinib: Results of Concentration‐QTc Analysis From a Thorough QT Study in Healthy Subjects

This thorough QT (TQT) study evaluated the effect of zanubrutinib on electrocardiogram (ECG) parameters by using concentration‐QTc (C‐QTc) analysis as the primary analysis for this study. Part A of the study determined the safety and tolerability of a single supratherapeutic dose of zanubrutinib (48...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Clin Transl Sci
Päätekijät: Mu, Song, Darpo, Borje, Tang, Zhiyu, Novotny, William, Tawashi, Manal, Xue, Hongqi, Willett, Michael, Lin, Leo, Sahasranaman, Sri, Ou, Ying C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2020
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7485941/
https://ncbi.nlm.nih.gov/pubmed/32144955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12779
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