Time dependent effect of cold ischemia on the phosphoproteome and protein kinase activity in fresh-frozen colorectal cancer tissue obtained from patients

BACKGROUND: Based on their potential to analyze aberrant cellular signaling in relation to biological function, kinase activity profiling in tumor biopsies by peptide microarrays and mass spectrometry-based phosphoproteomics may guide selection of protein kinase inhibitors in patients with cancer. V...

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Bibliografske podrobnosti
izdano v:Clin Proteomics
Main Authors: Buffart, Tineke E., van den Oord, Rosanne A. H. M., van den Berg, Adriënne, Hilhorst, Riet, Bastiaensen, Niek, Pruijt, Hans F. M., van den Brule, Adriaan, Nooijen, Peet, Labots, Mariette, de Goeij-de Haas, Richard R., Dekker, Henk, Piersma, Sander R., Pham, Thang V., van der Leij, Theo, de Wijn, Rik, Ruijtenbeek, Rob, Jiménez, Connie R., Verheul, Henk M. W.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7893972/
https://ncbi.nlm.nih.gov/pubmed/33602116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12014-020-09306-6
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