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Development of small-molecule tropomyosin receptor kinase (TRK) inhibitors for NTRK fusion cancers
Tropomyosin receptor kinase A, B and C (TRKA, TRKB and TRKC), which are well-known members of the cell surface receptor tyrosine kinase (RTK) family, are encoded by the neurotrophic receptor tyrosine kinase 1, 2 and 3 (NTRK1, NTRK2 and NTRK3) genes, respectively. TRKs can regulate cell proliferation...
Sparad:
| I publikationen: | Acta Pharm Sin B |
|---|---|
| Huvudupphovsmän: | , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Elsevier
2021
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7893124/ https://ncbi.nlm.nih.gov/pubmed/33643817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2020.05.004 |
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