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Methods for Identifying Patients with Tropomyosin Receptor Kinase (TRK) Fusion Cancer

NTRK gene fusions affecting the tropomyosin receptor kinase (TRK) protein family have been found to be oncogenic drivers in a broad range of cancers. Small molecule inhibitors targeting TRK activity, such as the recently Food and Drug Administration-approved agent larotrectinib (Vitrakvi®), have sho...

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Detalhes bibliográficos
Publicado no:Pathol Oncol Res
Main Authors: Wong, Derek, Yip, Stephen, Sorensen, Poul H.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7297824/
https://ncbi.nlm.nih.gov/pubmed/31256325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12253-019-00685-2
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