Relationship between CYP2D6 genotype, activity score and phenotype in a pediatric Thai population treated with risperidone

Recently, the Clinical Pharmacogenetics Implementation Consortium (CPIC) have revised recommendations for the translation of CYP2D6 genotype to phenotype. Changes affect phenotype grouping, as well as the value used to calculate activity score for the CYP2D6*10 allele to better reflect the substanti...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Hongkaew, Yaowaluck, Gaedigk, Andrea, Wilffert, Bob, Ngamsamut, Nattawat, Kittitharaphan, Wiranpat, Limsila, Penkhae, Sukasem, Chonlaphat
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2021
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7892547/
https://ncbi.nlm.nih.gov/pubmed/33603025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83570-w
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