Development and Validation of Liquid Chromatography/Tandem Mass Spectrometry Analysis for Therapeutic Drug Monitoring of Risperidone and 9‐Hydroxyrisperidone in Pediatric Patients with Autism Spectrum Disorders

BACKGROUND: Risperidone (RIS) is a widely used atypical antipsychotic drug. We developed and validated a sensitive and accurate LC‐MS/MS method, which requires a small‐volume of plasma and small‐volume injection for measurement of RIS levels in ASD pediatric patients. We also investigated the relati...

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Detalhes bibliográficos
Publicado no:J Clin Lab Anal
Main Authors: Vanwong, Natchaya, Prommas, Santirat, Puangpetch, Apichaya, Hongkaew, Yaowaluck, Nuntamool, Nopadol, Nakorn, Chalitpol Na, Ngamsamut, Nattawat, Limsila, Penkhae, Sukasem, Chonlaphat
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6807077/
https://ncbi.nlm.nih.gov/pubmed/27346210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.22009
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