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Relationship between CYP2D6 genotype, activity score and phenotype in a pediatric Thai population treated with risperidone

Recently, the Clinical Pharmacogenetics Implementation Consortium (CPIC) have revised recommendations for the translation of CYP2D6 genotype to phenotype. Changes affect phenotype grouping, as well as the value used to calculate activity score for the CYP2D6*10 allele to better reflect the substanti...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hongkaew, Yaowaluck, Gaedigk, Andrea, Wilffert, Bob, Ngamsamut, Nattawat, Kittitharaphan, Wiranpat, Limsila, Penkhae, Sukasem, Chonlaphat
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7892547/
https://ncbi.nlm.nih.gov/pubmed/33603025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83570-w
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