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An optimized workflow for CRISPR-Cas9 deletion of surface and intracellular factors in primary human T lymphocytes
The appropriate regulation of T lymphocyte functions is key to achieve protective immune responses, while at the same time limiting the risks of tissue damage and chronic inflammation. Deciphering the mechanisms underpinning T cell responses in humans may therefore be beneficial for a range of infec...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7891767/ https://ncbi.nlm.nih.gov/pubmed/33600503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247232 |
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