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An optimized workflow for CRISPR-Cas9 deletion of surface and intracellular factors in primary human T lymphocytes

The appropriate regulation of T lymphocyte functions is key to achieve protective immune responses, while at the same time limiting the risks of tissue damage and chronic inflammation. Deciphering the mechanisms underpinning T cell responses in humans may therefore be beneficial for a range of infec...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Leoni, Cristina, Bianchi, Niccolò, Vincenzetti, Lucia, Monticelli, Silvia
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7891767/
https://ncbi.nlm.nih.gov/pubmed/33600503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247232
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