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Oligosaccharides increase the genotoxic effect of colibactin produced by pks+ Escherichia coli strains

BACKGROUND: Colibactin is a genotoxin that induces DNA double-strand breaks that may lead to carcinogenesis and is produced by Escherichia coli strains harboring the pks island. Human and animal studies have shown that colibactin-producing gut bacteria promote carcinogenesis and enhance the progress...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Cancer
Prif Awduron: Oliero, Manon, Calvé, Annie, Fragoso, Gabriela, Cuisiniere, Thibault, Hajjar, Roy, Dobrindt, Ulrich, Santos, Manuela M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7890614/
https://ncbi.nlm.nih.gov/pubmed/33596864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-021-07876-8
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