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Iron Homeostasis Regulates the Genotoxicity of Escherichia coli That Produces Colibactin

The genotoxin colibactin is a secondary metabolite produced by a variety of pathogenic enterobacteria. Its biosynthesis requires the enzymatic activity of the phosphopantetheinyl transferase (PPTase) ClbA. We previously showed that ClbA can also contribute to the production of siderophores. Because...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Tronnet, Sophie, Garcie, Christophe, Rehm, Nadine, Dobrindt, Ulrich, Oswald, Eric, Martin, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116714/
https://ncbi.nlm.nih.gov/pubmed/27620723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00659-16
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