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Escherichia coli Producing Colibactin Triggers Premature and Transmissible Senescence in Mammalian Cells

Cellular senescence is an irreversible state of proliferation arrest evoked by a myriad of stresses including oncogene activation, telomere shortening/dysfunction and genotoxic insults. It has been associated with tumor activation, immune suppression and aging, owing to the secretion of proinflammat...

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Autori principali: Secher, Thomas, Samba-Louaka, Ascel, Oswald, Eric, Nougayrède, Jean-Philippe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792898/
https://ncbi.nlm.nih.gov/pubmed/24116215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077157
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