Ectopic expression of pericentric HSATII RNA results in nuclear RNA accumulation, MeCP2 recruitment, and cell division defects

Within the pericentric regions of human chromosomes reside large arrays of tandemly repeated satellite sequences. Expression of the human pericentric satellite HSATII is prevented by extensive heterochromatin silencing in normal cells, yet in many cancer cells, HSATII RNA is aberrantly expressed and...

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Detalhes bibliográficos
Publicado no:Chromosoma
Main Authors: Landers, Catherine C., Rabeler, Christina A., Ferrari, Emily K., D’Alessandro, Lia R., Kang, Diana D., Malisa, Jessica, Bashir, Safia M., Carone, Dawn M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7889552/
https://ncbi.nlm.nih.gov/pubmed/33585981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-021-00753-0
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