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A brain-derived MeCP2 complex supports a role for MeCP2 in RNA processing

Mutations in MECP2 (methyl CpG binding protein 2) are linked to the severe postnatal neurodevelopmental disorder Rett Syndrome (RTT). MeCP2 was originally characterized as a transcriptional repressor that preferentially bound methylated DNA, however, recent data indicates MeCP2 is a multifunctional...

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Autors principals: Long, Steven W., Ooi, Jenny Y. Y., Yau, Peter M., Jones, Peter L.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148018/
https://ncbi.nlm.nih.gov/pubmed/21070191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20100124
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