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Targeting the Opening of Mitochondrial Permeability Transition Pores Potentiates Nanoparticle Drug Delivery and Mitigates Cancer Metastasis

Mitochondria are highly involved in the metastasis of cancer cells. However, low permeability of mitochondria impedes the entry of anti‐cancer drugs. Here, a self‐assembled nanoparticle platform is designed that not only targets the DNA‐intercalating agent doxorubicin to mitochondria but also enhanc...

詳細記述

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書誌詳細
出版年:Adv Sci (Weinh)
主要な著者: Lin, Xi, Li, Lian, Li, Shujie, Li, Qiuyi, Xie, Dandan, Zhou, Minglu, Huang, Yuan
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7887600/
https://ncbi.nlm.nih.gov/pubmed/33643797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202002834
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