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Targeting the Opening of Mitochondrial Permeability Transition Pores Potentiates Nanoparticle Drug Delivery and Mitigates Cancer Metastasis
Mitochondria are highly involved in the metastasis of cancer cells. However, low permeability of mitochondria impedes the entry of anti‐cancer drugs. Here, a self‐assembled nanoparticle platform is designed that not only targets the DNA‐intercalating agent doxorubicin to mitochondria but also enhanc...
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| Pubblicato in: | Adv Sci (Weinh) |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7887600/ https://ncbi.nlm.nih.gov/pubmed/33643797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202002834 |
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