The tyrosine kinase c-Abl potentiates interferon-mediated antiviral immunity by STAT1 phosphorylation

Interferon (IFN)-induced activation of the signal transducer and activator of transcription (STAT) family is an important event in antiviral immunity. Here, we show that the nonreceptor kinases c-Abl and Arg directly interact with STAT1 and potentiate the phosphorylation of STAT1 on Y701. c-Abl/Arg...

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Vydáno v:iScience
Hlavní autoři: Liu, Hainan, Cui, Yan, Bai, Yu, Fang, Yi, Gao, Ting, Wang, Guangfei, Zhu, Lin, Dong, Qincai, Zhang, Shuwei, Yao, Yi, Song, Caiwei, Niu, Xiayang, Jin, Yanwen, Li, Ping, Cao, Cheng, Liu, Xuan
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7887405/
https://ncbi.nlm.nih.gov/pubmed/33644712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102078
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