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Parainfluenza Virus 3 Blocks Antiviral Mediators Downstream of the Interferon Lambda Receptor by Modulating Stat1 Phosphorylation

Parainfluenza viruses are known to inhibit type I interferon (IFN) production; however, there is a lack of information regarding the type III IFN response during infection. Type III IFNs signal through a unique heterodimeric receptor, IFN-λR1/interleukin-10R2 (IL-10R2), which is primarily expressed...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Eberle, Kirsten C., McGill, Jodi L., Reinhardt, Timothy A., Sacco, Randy E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810625/
https://ncbi.nlm.nih.gov/pubmed/26719274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02502-15
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