Depot medroxyprogesterone acetate (DMPA) enhances susceptibility and increases the window of vulnerability to HIV-1 in humanized mice

The progestin-based hormonal contraceptive Depot Medroxyprogesterone Acetate (DMPA) is widely used in sub-Saharan Africa, where HIV-1 is endemic. Meta-analyses have shown that women using DMPA are 40% more likely than women not using hormonal contraceptives to acquire Human Immunodeficiency Virus (H...

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Publicat a:Sci Rep
Autors principals: Wessels, Jocelyn M., Nguyen, Philip V., Vitali, Danielle, Mueller, Kristen, Vahedi, Fatemeh, Felker, Allison M., Dupont, Haley A., Bagri, Puja, Verschoor, Chris P., Deshiere, Alexandre, Mazzulli, Tony, Tremblay, Michel J., Ashkar, Ali A., Kaushic, Charu
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7887257/
https://ncbi.nlm.nih.gov/pubmed/33594113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83242-9
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