Depot medroxyprogesterone acetate (DMPA) enhances susceptibility and increases the window of vulnerability to HIV-1 in humanized mice

The progestin-based hormonal contraceptive Depot Medroxyprogesterone Acetate (DMPA) is widely used in sub-Saharan Africa, where HIV-1 is endemic. Meta-analyses have shown that women using DMPA are 40% more likely than women not using hormonal contraceptives to acquire Human Immunodeficiency Virus (H...

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Publicado no:Sci Rep
Main Authors: Wessels, Jocelyn M., Nguyen, Philip V., Vitali, Danielle, Mueller, Kristen, Vahedi, Fatemeh, Felker, Allison M., Dupont, Haley A., Bagri, Puja, Verschoor, Chris P., Deshiere, Alexandre, Mazzulli, Tony, Tremblay, Michel J., Ashkar, Ali A., Kaushic, Charu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7887257/
https://ncbi.nlm.nih.gov/pubmed/33594113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83242-9
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