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Gα(q) and the Phospholipase Cβ3 X–Y Linker Regulate Adsorption and Activity on Compressed Lipid Monolayers

Phospholipase Cβ (PLCβ) enzymes are peripheral membrane proteins required for normal cardiovascular function. PLCβ hydrolyzes phosphatidylinositol 4,5-bisphosphate, producing second messengers that increase intracellular Ca(2+) level and activate protein kinase C. Under basal conditions, PLCβ is aut...

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Bibliografiske detaljer
Udgivet i:Biochemistry
Main Authors: Hudson, Brianna N., Jessup, Rachel E., Prahalad, Keshav K., Lyon, Angeline M.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885793/
https://ncbi.nlm.nih.gov/pubmed/31322863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00441
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